what effect does deprivation of dietary pyridoxal phosphate have on the capacity to metabolize amino acids? explain
Pyridoxal phosphate is a cofactor required for the activity of transaminases.
It is also required for the biosynthesis of neurotransmitters and sphingolipids.
It serves as a coenzyme for glycogen phosphorylase and ALA synthase.
Transaminases are an important group of enzymes involved in the amino acid metabolism. They mediate the transfer of amino groups.
Alanine + Alpha-ketoglutarate ----------> Pyruvate + Glutamate
Deficiency symptoms:
i. Glossitis
ii. Angular cheilitis
iii. Conjunctivitis
iv. Sideroblastic anemia
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