Question

what effect does deprivation of dietary pyridoxal phosphate have on the capacity to metabolize amino acids?...

what effect does deprivation of dietary pyridoxal phosphate have on the capacity to metabolize amino acids? explain

Homework Answers

Answer #1

Pyridoxal phosphate is a cofactor required for the activity of transaminases.

It is also required for the biosynthesis of neurotransmitters and sphingolipids.

It serves as a coenzyme for glycogen phosphorylase and ALA synthase.

Transaminases are an important group of enzymes involved in the amino acid metabolism. They mediate the transfer of amino groups.

Alanine + Alpha-ketoglutarate ----------> Pyruvate + Glutamate

Deficiency symptoms:

i. Glossitis

ii. Angular cheilitis

iii. Conjunctivitis

iv. Sideroblastic anemia

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