Question

A patient is on the direct thrombin inhibitor dabigatran due to a blood clot. The physician...

A patient is on the direct thrombin inhibitor dabigatran due to a blood clot. The physician orders a lupus anticoagulant work-up. The dRVVT ratio is 1.9. The patient has a lupus anticoagulant. true or false ....

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Answer #1

True, Because Lupus anticoagulants are autoantibodies produced by the immune system that mistakenly attack certain components of the body's own cells. They specifically target phospholipids as well as the proteins associated with phospholipids that are found in the outer-most layer of cells (cell membranes). These autoantibodies interfere with the blood clotting process in a way that is not fully understood and increase a person's risk of developing a blood clot. Lupus anticoagulant testing is a series of tests that detect the presence of lupus anticoagulant in the blood.

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