Question

What are the two major differences between the structure of eukaryotic and prokaryotic chromosomes, and how does this affect DNA replication?

Answer 1

In prokaryotes , there is no telomeres in Chromosome . While eukaryotes have.

And there is no histones on the chromosome and it is not organised into nucleosome. While eukaryotes have histone proteins and their dna is organised into nucleosome.

Effect on DNA replication-

Following are not needed in prokaryotes.

There is no need of telomerase enzyme for telomeres replication due to end Dna replication problem.

There is no need to unwind nucleosome and condensation of DNA into chromosome and then doubling the nucleosome as amount of DNA has been doubled.