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Cytotoxic T cells are very important for defense against viruses. What protein presents antigen to cytotoxic...

Cytotoxic T cells are very important for defense against viruses. What protein presents antigen to cytotoxic T cells and what protein on the T cell recognizes the antigen? Bonus points: which CD marker is on all T cells and what is only on cytotoxic T cells?

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Answer #1

T cell receptor recognised and bind to the antigen associated with MHC. CD4 is present on the helper T cell whereas CD8 is present on the cytotoxic T cell surface.

Antigen bind to the MHCII molecule is recognised by the CD4 present on the helper T cell and secrete the cytokine in order to activate the B cell proliferation and stimulate antibodies production.

Antigen bind to the MHCI molecule is recognised by the CD8 present on the cytotoxic T cell and kill the target cell.

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