Question

Which of the following is TRUE of the humoral immune response and NOT true of the cell-mediated immune response. Only the humoral immune response _______.

A) invovles T cells at some level

B) requires CD8+ cells for activation

C) requires CD4 cells for activation

D) involves destroying the entire cell and not just the pathogen

E) uses antibodies as its main weapon

Answer 1

T cell not synthesizes antibodies but instead synthesize and release cytokines that affect other cells. Hence this acquired immune response is termed as cellular or cell-mediated immunity. T cell express distinct membrane molecules. On the basis of the presence of one or the other two membrane molecules, CD4+ and CD8+, there is two subpopulation of T cells- T helper cells, TH and T cytotoxic cells, TC.

While coming to humoral immune response, mediated mainly by B cells and circulating antibodies. They are the only cell type capable of producing antibody molecules and therefore the central cellular component of the humoral immune response.

Therefore option e is correct. Uses antibodies as its main weapon.