Question

Explain why it is generally easier to control (with antimicrobial chemicals) a bacterial pathogen in the human body than it is to control a fungal pathogen in the human body.

Answer 1

# In general we use antibiotics to control or kill the growth of an organism. Bacterium is a prokaryote and Fungus is a eukaryote. Human also eukaryote. Most of antibiotics that we use to kill the bacteria are inhibiting the growth by blocking the protein synthesis. Usually most of the of the antibiotics bind with the ribosomal subunits such as 50S and 30S of prokaryotes but, we have 60S and 40S. Therefore, those antibiotics will be highly specific for the prokaryotes only. They don't have much effect on the human metabolism.

But this is not same in the case of fungus. Anything you give to kill a fungus will have serious effect on human also becuase, both have same mechanism for most of the metabolism (transcription, translation, etc). That is why it is very difficult to control a fungal pathogen in human body than a bacterium.