Question

1. An individual whose pancreas cannot produce insulin will have difficulty assimilating blood glucose into which one of the following tissues?

1. Brain cells
2. Adipocytes
3. Red blood cells
4. Liver cells (hepatocytes)
5. Intestine cells

Answer 1

An individual whose pancreas cannot produce insulin will have difficulty assimilating blood glucose into the following tissue :-

(b) Adipocytes

Assimilation of blood glucose into the tissues require Glucose Transporters (GLUT). Since the individual's pancreas cannot produce insulin so GLUT-4 will not be able to work properly.

GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The principal glucose transporter protein that mediates this uptake is GLUT4, which plays a key role in regulating whole body glucose homeostasis. So there will be difficulty in assimilating blood glucose in adipose tissues.

Other options are incorrect since they do not require insulin dependant glucose transporter (GLUT-4) and thus assimilation is not affected in brain cells, Red blood cells, hepatocytes & intestinal cells.

Glucose transporters in :-

Brain cells :- GLUT-1

Red blood cells :- GLUT-1

Hepatocytes :- GLUT-2

Intestinal cells :- GLUT-2

Only GLUT-4 is insulin dependant so other glucose transporters will not be affected in insulin deficiency.

Thus the correct answer is (b) Adipocytes.