The activity site of ribonucleotide reductase can bind two different molecules, whereas the specificity site can bind several. Construct a situation where the activity of the enzyme is inhibited by choosing the identity of the molecules bound to each site.
From the above mentioned conditions we can say that the activity of the enzyme can be inhibited by two ways:
Competitive inhibition and allosteric inhibition.
In case of competitive inhibition,the inhibitor which has close structural similarities with the substrate binds at the active site of the enzyme and prevents the binding of the substrate with the active site of the enzyme,thus inhibiting the activity of the enzyme.
In case of allosteric inhibition,the inhibitor binds to a site other than the active site of the enzyme which causes a confirmational change in the enzyme so that substrate cannot bind to the active site of the enzyme,thus inhibiting the activity of the enzyme.
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