Question

Why is permeability of the intermembrane space of the mitochondria so tightly regulated?

Question 18 options:

A	concentration of Pi (inorganic phosphate) in the matrix needs to be kept low
B	prevents pyruvate entry into intermembrane space
C	concentration of ADP in the matrix needs to be kept low
D	energy would be lost if protons could flow down their concentration gradient

Answer 1

Ans is D as the proton is pumped into intermembrane space and gradient is achieved which is used by ATPsynthase by allowing the passing of proton through it and making ATP through this process if the intermembrane space permeability is increased then the proton gradient won't get formed and the formation of ATP would not occur which is the energy currency of cell . Without the currency system can't work in the same way without ATP cells can't work we will die. That's why its permeability must be tightly regulated.

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