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Explain why babies with agammaglobulinemia do not develop opportunistic infections until about 6 months after birth...

Explain why babies with agammaglobulinemia do not develop opportunistic infections until about 6 months after birth


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Answer #1

Agammaglobulinemia is an immune system disorder characterized by a low concentrations of antibodies in the blood.

IgG can cross the placenta to provide maternal antibodies to the new born.
the most abundant antibody found in the breast milk = IgA
All the other types are found in minute quntities.

Babies with agammaglobulinemia do not develop opportunistic infections until about 6 months after birth due to the presence of maternal antibodies in their system. After 4-6 months, the level of maternal antibodies decreases in the child's system making them susceptible to invading pathogens.


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