Question

8. Mitochondria operate to keep the concentration of oxaloacetate very low. The ?G for the reaction:...

8. Mitochondria operate to keep the concentration of oxaloacetate very low. The ?G for the reaction: malate + NAD+ ? oxaloacetate + NADH is about + 29 kJ/mol. Why is it important to keep the concentration of oxaloacetate so low?

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

The first step in TCA cycle formation of citrate from oxaloacetate and acetyl-CoA is controlled by the concentration of acetyl-CoA. The concentration of oxaloacetate also most important since it is very low in mitochondria.
Citrate is a competitive inhibitor for oxaloacetate on the enzyme. Because the cycle has to function at the same rate to restore the OAA consumed in the first step. If any product is increased or accumulate in the cycle leads to decrease in OAA.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Which of the following statements about DNA repair is correct during excision repair, an exonuclease is...
Which of the following statements about DNA repair is correct during excision repair, an exonuclease is the first enzyme involved in removing a single-stranded segment of DNA from the template strand none of the answer is correct during mismatch repair, a methylated guanine in the consensus sequence GATC found on the parent strand activates the Mut complex the Okazaki fragments synthesized during base excision repair are synthesized in a 3’ -- > 5’ fashion repair of methylated DNA requires a...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions in response to the environment b. Generation of a chemical change in response to information c. Induction of cell death upon nutrient starvation d. Responses to stimuli 2. Which statement is correct? a. G protein-coupled receptors produce second messengers indirectly while receptor enzymes catalyse second messenger generation b. Second messengers stimulate the activity of G protein-coupled receptors. c. Receptor enzymes produce second messengers through...
Procedure I. Reverse Transcription. For each of your RNA samples set up the following reaction: *Remember...
Procedure I. Reverse Transcription. For each of your RNA samples set up the following reaction: *Remember to use proper RNA handling technique! 1. In a 0.2 ml size RNAse-Free tube add the following: • 0.5 µg RNA (no more than 6 µl) You can add as little as 0.1 µg of RNA if your concentration is low • 2 µl dT primer • Nuclease Free Water to final volume of 8 µl * Before you start write the exact volume...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
Acid-Base Behavior In addition to following the general safety rules, chemicals need to be handled properly....
Acid-Base Behavior In addition to following the general safety rules, chemicals need to be handled properly. In particular, two very important classes of compounds called acids and bases require special attention. These compounds are commonly used reagents in the laboratory; therefore, understanding their proper disposal is beneficial. Physical differences between acids and bases can be detected by the some of the five senses, including taste and touch. Acids have a sour or tart taste and can produce a stinging sensation...
1) Describe an example of each of the following that may be found of your kitchen:...
1) Describe an example of each of the following that may be found of your kitchen: Explain how your choice falls into this category, and if there is a chemical name or symbol for it, provide that as well. Provide a photo of your example with your ID card in it. a) a compound b) a heterogeneous mixture c) an element (symbol) Moving to the Caves… Lechuguilla Caves specifically. Check out this picture of crystals of gypsum left behind in...
QUESTION 1 1. Brianna is trying to increase her chances of being promoted to vice president...
QUESTION 1 1. Brianna is trying to increase her chances of being promoted to vice president by working to build good work relationships with other managers outside her own department. Brianna's behavior should be viewed as dysfunctional politics. functional politics. coercive power. functional influence. 2 points QUESTION 2 1. The Gingerbread Factory has a separate unit that makes their chocolate crunch cookies and another unit that is completely responsible for all operations in producing their ginger snap cookies. The Gingerbread...
What tools could AA leaders have used to increase their awareness of internal and external issues?...
What tools could AA leaders have used to increase their awareness of internal and external issues? ???ALASKA AIRLINES: NAVIGATING CHANGE In the autumn of 2007, Alaska Airlines executives adjourned at the end of a long and stressful day in the midst of a multi-day strategic planning session. Most headed outside to relax, unwind and enjoy a bonfire on the shore of Semiahmoo Spit, outside the meeting venue in Blaine, a seaport town in northwest Washington state. Meanwhile, several members of...
Please read the article and answear about questions. Determining the Value of the Business After you...
Please read the article and answear about questions. Determining the Value of the Business After you have completed a thorough and exacting investigation, you need to analyze all the infor- mation you have gathered. This is the time to consult with your business, financial, and legal advis- ers to arrive at an estimate of the value of the business. Outside advisers are impartial and are more likely to see the bad things about the business than are you. You should...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT