Question

There are two types of twins, monozygotic (identical) twins where the offspring are generated from the unexpected splitting of the same fertilised egg, while dizygotic (fraternal) twins arise from independent fertilisations of two different eggs. Discuss the power of STR profiling in discriminating between monozygotic and dizygotic twins [2-3 sentences].

Answer 1

Ans.

*STR* is a Short tandem Repeat.It consists of 3 steps:-

1. Amplification

2. Electrophoresis

3. Interpretation

These STR loci (locations on a chromosome) are targeted with sequence-specific primers and amplified using PCR.

STR have low mutation rate and due to that data more stable and predictable.Therefore, STRs with higher power of discrimination chosen for human identification in forensic cases on a regular basis. It is used to identify victim, perpetrator, missing persons, and others.