How do the cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase differ from each other? Please explain in detail.
Difference between cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase
Cytosolic glycerol 3-phosphate dehydrogenase | Mitochondrial glycerol 3-phosphate dehydrogenase |
Also called GPD1 | Also called GPD2 |
GPD1 located on the inner-membrane space or cytosol of mitochondrial | Located on the outer surface of the inner mitochondrial membrane |
Catalyzes the formation of glycerol-3-phosphate by reducing dihydroxyacetone phosphate | Catalyse the formation of dihydroxyacetone phosphate by the oxidation of glycerol-3-phosphate |
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