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How do the cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase differ from each other? Please...

How do the cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase differ from each other? Please explain in detail.

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Answer #2

Difference between cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase

Cytosolic glycerol 3-phosphate dehydrogenase Mitochondrial glycerol 3-phosphate dehydrogenase
Also called  GPD1 Also called GPD2
GPD1 located on the inner-membrane space or cytosol of mitochondrial Located on the outer surface of the inner mitochondrial membrane
Catalyzes the formation of glycerol-3-phosphate by reducing dihydroxyacetone phosphate Catalyse the formation of dihydroxyacetone phosphate by the oxidation of glycerol-3-phosphate
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