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A true breeding agouti (brownish color) mouse is crossed to a true breeding albino mouse. The...

A true breeding agouti (brownish color) mouse is crossed to a true breeding albino mouse. The F1 generation is all agouti. When members of the F1 are interbred the following types of mice are obtained in the F2 generation:

agouti              180

albino              80

black               60

How many genes control color in these mice? How many alleles for each gene? Explain your answer (in one sentence).   

What are the genotypes corresponding to each of the three phenotypes? Explain. Be sure to clearly indicate the alleles that are dominant and the alleles that are recessive.   

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Answer #1

2 genes control the coat colour

there are 2 alleles for each gene

it is an example of recessisve epistasis

when we take out the ratio of agouti :albino: black=180:80:60=9:4:3

in this allele A is hypostatic to allele c

genotype

agouti=AACC,AaCC,AACcAaCc(when both A and C are dominant)

albino=aacc,AAcc,Aacc(cc gives albino mice regardless of A gene alleles)

black=aaCC,aaCc(when C is dominant and A is recessisve)

A is dominant over a and C is dominant over c

cc is epistatic it hides the expression of A regardless of being dominant or recessive allele

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