Question

Given the Normal DNA Sequence: 5’ –ATG ATC AGA CTA GCT CAC TCG GGA GTG TGA… 3’

Determine what type of mutation occurred in the following mutant DNA.

Mutant II: 5’ –ATG ATC AGA CTA GCT CGC TCG GGA GTG TGA… 3’

a. At what codon number did mutation occurred?

b. Identify the type of substitution point mutation happened

c. What is the resulting amino acid of the codon that was mutated?

d. What is the consequence of that mutation?

Answer 1

Ans- a At the 6th position, means at the 6 th codon from 5' side the mutation has occurred.

Ans-b The type of substitution point mutation is known as missense mutation.

Ans- c mutated codon- C​​​​​​G​​​​​C

So on mRna , the sequence will be - G​​​​​​C​​​​​G

The resulting amino acid is Alanine.

Ans- d The consequence of this mutation is that a different amino acid is produced instead of right one. The protein that is being produced will alter the whole sequence and different protein will be produced.

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