Question

Tumor cells produce high levels of PD-1 to absorb PD-L1 produced by immune cells. A)  True     B)  False

Tumor cells produce high levels of PD-1 to absorb PD-L1 produced by immune cells.

A)  True    

B)  False

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

(B) False.

Tumor cells produce PD-L1 to absorb PD-1 produced by immune cells.

PD-L1 is expressed on the surface of tumor cells and then they bind to PD-1 on the surface of activated T cells and B cells. This binding of PD-L1 to PD-1 leads to immunosuppressive effect and allows the tumor to immune destruction.

PD-1 or programmed cell death-1 receptor is present on the surface of activated T cells. The activated T cells recognise and bind to the cancer cells. The bound effector T cells release cytotoxins, which induce apoptosis in their target cancer cells. PD-L1 expressed on the tumor cells binds to PD-1 receptors on the activated T cells, which leads to the inhibition of the cytotoxic T cells.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Tumor cells produce high levels of PD-1 to absorb PD-L1 produced by immune cells. True or...
Tumor cells produce high levels of PD-1 to absorb PD-L1 produced by immune cells. True or False
Besides the existence of tumor-specific T cells and B cells, many studies have demonstrated that high...
Besides the existence of tumor-specific T cells and B cells, many studies have demonstrated that high numbers of tumor-infiltrating lymphocytes are associated with good clinical outcome. In addition, not only the density but also the organization of tumor-infiltrating immune cells has been shown to determine cancer patient survival. Indeed, more and more studies describe the development within the tumor microenvironment of this anatomic micro-structure, whose presence has a positive impact on tumor prognosis. What is it?
1- Atoms absorb all wavelengths of light that incident on them a- True b- False 2-...
1- Atoms absorb all wavelengths of light that incident on them a- True b- False 2- Atoms of different elements have different energy levels for electrons a- True b- False
true  false   A high concentration of a hormone in the blood triggers signal amplification in all body cells....
true  false   A high concentration of a hormone in the blood triggers signal amplification in all body cells. true  false   A hormone must bind to a receptor to cause a response in a target cell. true  false   Hormones can produce the same response in different target cells.
anatomy True and F question 1. Memory B-cells kill bacteria with perforin proteins. True False 2....
anatomy True and F question 1. Memory B-cells kill bacteria with perforin proteins. True False 2. Cytotoxic T-cells kill bacteria with perforin proteins. True False 3. Memory B-cells form the basis of long-lived immunity. True False 4. Leukocytoblasts form platelets True False 5. Smooth muscle is responsible for vasodilation. True False 6. Smooth muscle is responsible for vasoconstriction. True False 7. The heart exhibits autorhymicity. Group of answer choices True False 8. The fossa ovalis is a weak spot in...
True or false.  NSO murine myeloma cells are used in a bioreactor to produce the pharmaceutical Tysabri....
True or false.  NSO murine myeloma cells are used in a bioreactor to produce the pharmaceutical Tysabri. Please explain!
1. True or False : Several oncogenes encode antiapoptotic proteins that promote cell survival 2. True...
1. True or False : Several oncogenes encode antiapoptotic proteins that promote cell survival 2. True or False: Cancer Patients with mutant p53 can be treated effectively with radiation therapy 3. Tumor promoter is a type of carcinogen that a. decreases chromosomal stability b. increases cell proliferation c. induces apoptosis of healthy cells d. immortalizes cancer cells 4. Tumor initiation occurs in a a. single cell b. few cells c. single protein molecule d. single tissue 5. True or False:...
1. ON/OFF ganglion cells project to the contralateral LGN True False 2. Indicate which cells produce...
1. ON/OFF ganglion cells project to the contralateral LGN True False 2. Indicate which cells produce action potentials Bipolar cell Ganglion cell Photoreceptor 3. Some ganglion cells which respond to color have center-surround receptive fields. This supports the _____ view of color perception Opponent processes Mixing 4. Imagine that your visual field is filled by a gray background, with a pinpoint position in the upper right quadrant we will the “target spot”, which falls in your eyes fovea. Now suppose...
9.Myeloid cells produced from haemapoietic stem cells will all be white blood cells. Select one: True...
9.Myeloid cells produced from haemapoietic stem cells will all be white blood cells. Select one: True False 10. Which of the following statements is true? Select one: a. Infected body cells are an example of antigen presenting cells (APCs). b. A CD8+ T cell will bind to intact pathogens circulating in the blood. c. Phagocytes only destroy virally-infected cells. d. In the absence of an antigen, a B cell incubated with Th cytokines will proliferate into memory B cells and...
1) Superantigens cross link T cells with APC in a polyclonal, non specific fashion. a. True...
1) Superantigens cross link T cells with APC in a polyclonal, non specific fashion. a. True b. False 2) cross presentation of antigens in a special circumstance only allowed in cells that become licensed to activate Tc cells. a. True b. False 3) central tolerance refers to T cells that become anergic in centrally located tissues. a. True b. False 4) activated Th cells express the cytokine IL-2 and the high affinity receptor for IL-2.  a. True b. False
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT