Question

There are two codons for the amino acid lysine: 5’-AAA-3’ and 5’-AAG-3’. Which of the following tRNA anticodon sequences would be able to recognize both of these codons?

Group of answer choices

5’-UUU-3’

5’-UUC-3’

5’-CUU-3’

5’-IUU-3’

Question 471 pts

There are six codons for the amino acid arginine. Three of these codons are:

5’-CGC-3’
5’-CGU-3’
5’-CGA-3’

Which of the following anticodons would be able to recognize all three of these codons?

Group of answer choices

5’-ACG-3’

5’-GCG-3’

5’-UCG-3’

5’-ICG-3’

5’-GCI–3’

There is only one codon for methionine, and it reads 5'-AUG-3'. What is the sequence of the anticodon in the corresponding tRNA?

Group of answer choices

5'-AUG-3'

5’-CAU-3’

5’-UAC-3’

Answer 1

Answer: 5'- UUU -3'

Question 471 pts

Answer: 5' - ICG - 3'

Answer: 5' - CAU - 3'

Explanation:

Wobble effect is the compromised deviation from the standard Watson-Crick base pairing which can occur during the codon-anticodon base pairing. During wobble, the pairing between the third base (on the 3' side) of a codon (shown in bold 5'-N N N-3' ) and the first base (on the 5' side) of anticodon can deviate from the standard base pairing rules.

After wobble, the following pairings are allowed:

Anticodon      Codon      

G                     U , C

C                       G

A                       U

U                     A , G

I                      U , C , A

Here, I stands for inosine which resembles G (guanosine). It is a modified base found in the tRNA

An example of wobble pairing is as follows:

Codon         5' U U U 3'

Anticodon    3' A A G 5'

Here, we see that G is pairing with U which is a deviation from the standard Watson-Crick pairing rule

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