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Can you write this aspects of Nicergolina (used against Ateroesclerosis) *Bioavailability *Volume of distribution *Average life...

Can you write this aspects of Nicergolina (used against Ateroesclerosis)

*Bioavailability
*Volume of distribution
*Average life
*Metabolism
*Excretion (clarification)

(In computer please, I can't understand some penmanships)
Thanks

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Answer #1

Aspects of Nicergolina (used against Ateroesclerosis)

1.Bioavailability:- <5% (less than 5%)

2.Volume of distribution -30 mg/box

3.Average Life- 15 to 20 hours

4. Metabolism- Extensive first pass metabolism.

5. Excretion- It is excreted by a urine and faeces.Via urine it is excreted 80% and through faeces 20%,In all species nicergoline is extensively metabolised in the body and the final products, labelled 1,6-dimethyl-8β -hydroxymethyl-10α-methoxyergoline and 8β -hydroxymethyl - 10α-methoxy -6-methylergoline, as well as their glucuronides are excreted mainly by the kidneys

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