Question

Explain the formation of thioether-linked prenyl anchor proteins.

Explain the formation of thioether-linked prenyl anchor proteins.

Homework Answers

Answer #1

Thioether-linked prenyl anchors.

Farnesyl and geranylgeranyl groups are polymers of isoprene units that can attached to proteins at a cysteine residue. The cysteine to be modified is part of a carboxyl terminal recognition sequence of Cys-Ala-Ala-X.

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