Question

Which antibiotic would not be effective if bacteria produces beta lactamase?

A. Ketocanazole

B. Erythromycin

C. Penicillin

D. Sulpha trimethoprim

E. All of the above

Penicillinase target:

A. Folic acid

B. Bacterial cell wall

C. Protein

D. Beta lactam ring

Answer 1

Some Gram negative bacteria often produce beta - lactase enzyme, that provides multi resistance to some antibiotics which contain beta lactam ring. This enzymes break the beta lactam ring and deactivate the antibacterial properties of the antibiotics. The beta lactam antibiotic includes penicillins, cephalosporins, cephamycins and carbapenems.

**If bacteria produces beta lactamase, the antibiotic that would not be effective is that - - a. Ketocanazol.. Because it is an antifungal drug. Erythromycin have a similar structure and function like cephamycin, and penicillin and sulpha trimethoprim are beta lactam antibiotics. So, if bacteria produces beta lactamase erythromycin, penicillin and sulpha trimethoprim will be effective.

** Penicillinase is a type of beta lactamase, so penicillinase target - - D. Beta lactam ring...