Question

While it is widely believed that the GTPase Rheb directly activates mTORC1, the ability of PA...

While it is widely believed that the GTPase Rheb directly activates mTORC1, the ability of PA (18:1-16:0) to activate mTORC1 in the absence of Rheb strongly suggests that it is the ability of Rheb to activate PLD that is the last step in the activation mTORC1. A) True B) False

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

True

mTOR, mammalian target of Rapamycin is involved in the signalling cascade for the regulation of cell growth and proliferation in response to hormones and amino acids.Phospholipase D and it's product phoshpatidic acid are the upstream regulators of mTOR signalling.Rag GTPase helps in translocation of mTOR from cytoplasm to lysosome.PLD 1 on stimulus from amino acids activates mTOR.Rheb activates PLD 1 in the absence of mitogenic stimulation.PLD 1 as the studies suggest is an effector of Rheb.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
While it is widely believed that the GTPase Rheb directly activates mTORC1, the ability of PA...
While it is widely believed that the GTPase Rheb directly activates mTORC1, the ability of PA (18:1-16:0) to activate mTORC1 in the absence of Rheb strongly suggests that it is the ability of Rheb to activate PLD that is the last step in the activation mTORC1. True or Flase
1.) True or False? For all societies, resources are scarce, and technology is limited, while people’s...
1.) True or False? For all societies, resources are scarce, and technology is limited, while people’s wants and needs for goods and services seem to be unlimited. (2 points) 2.) (1 point) Adam Smith’s “invisible hand” refers to a.) the subtle and often hidden methods that businesses use to profit at consumers’ expense. b.) the ability of free markets to reach desirable outcomes, despite the self-interest of market participants. c.) the ability of government regulations to benefit consumers, even if...
5.Paralanguage includes yawning and laughing. True False 6.A person with the director style of communication likes...
5.Paralanguage includes yawning and laughing. True False 6.A person with the director style of communication likes to know the whole picture and thrives on details. True False 7.Effective feedback is evaluative rather than descriptive. True False 8.Social cognitive theory posits that humans often evaluate themselves quite differently than others do. True False 9.Vertical communication is required to make a coordinated, cross functional effort in achieving organizational goals. True False 10.The informal system of communication has a highly impersonal orientation. True...
1. Evidence that relates to, or bears directly upon, the point or fact in issue, and...
1. Evidence that relates to, or bears directly upon, the point or fact in issue, and proves or has a tendency to prove the proposition alleged, is relevant evidence. T OR F? 2. Evidence is legally material and admissible if it relates to a fact in issue and has only a slight bearing on the matter in issue. T OR F? 3. Photographic evidence of a gruesome crime scene may be admitted if it is probative of a fact in...
BIOCHEMISTRY ASSIGNMENT Please use your understanding to address the few concerns below * Required Index Number:...
BIOCHEMISTRY ASSIGNMENT Please use your understanding to address the few concerns below * Required Index Number: * Your answer Program: Choose BSc Midwifery BSc Nursing 1.When starch and amylase are mixed in the presence of iodine solution, the blue-black colour rapidly disappears. This is due to the formation of which molecule? * a) glucose b) glycogen c) sucrose d) maltose 2.Which of the following enzyme groups can catalyse oxidation reactions? * a) phosphorylases b) isomerases c) hydrolases d) dehydrogenases 3.Enzymes...
When is a hypothesis considered scientific? a. when it is based on something other than observation...
When is a hypothesis considered scientific? a. when it is based on something other than observation b. when it can be tested and is refutable c. when it relies on anecdotal evidence d. when it relies on mystical explanations e. All hypotheses are considered scientific until experiments determine otherwise. 3. Of the following, which is the earliest step in the scientific process? a. generating a hypothesis b. analyzing data c. conducting an experiment d. drawing a conclusion e. developing a...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions...
1. Which sentence best defines signal transduction in a biochemical context? a. Alteration of cell functions in response to the environment b. Generation of a chemical change in response to information c. Induction of cell death upon nutrient starvation d. Responses to stimuli 2. Which statement is correct? a. G protein-coupled receptors produce second messengers indirectly while receptor enzymes catalyse second messenger generation b. Second messengers stimulate the activity of G protein-coupled receptors. c. Receptor enzymes produce second messengers through...
QUESTION 1 1. Brianna is trying to increase her chances of being promoted to vice president...
QUESTION 1 1. Brianna is trying to increase her chances of being promoted to vice president by working to build good work relationships with other managers outside her own department. Brianna's behavior should be viewed as dysfunctional politics. functional politics. coercive power. functional influence. 2 points QUESTION 2 1. The Gingerbread Factory has a separate unit that makes their chocolate crunch cookies and another unit that is completely responsible for all operations in producing their ginger snap cookies. The Gingerbread...
Question 1 Which need in Maslow's hierarchy reflects a desire for love, friendship, affiliation, and group...
Question 1 Which need in Maslow's hierarchy reflects a desire for love, friendship, affiliation, and group acceptance? A.      Safety B.      Self-actualization C.      Belongingness D.      Esteem Question 2 If a person does not feel accepted or loved, they have not reached what level, according to Maslow ? A.      Level 1 B.      Level 5 C.      Level 3 D.      Level 2 Question 3 What stage of Maslow’s pyramid do you think could be skipped to move to another level ? A.      Psychological needs...
Answer True or False: 1. Classification criteria for economic system include decision-making systems, mechanisms for information...
Answer True or False: 1. Classification criteria for economic system include decision-making systems, mechanisms for information and coordination, incentive structures, property rights, and mechanisms for public choices. 2. All economic systems can be classified as market capitalism or centrally planned socialism. 3. Generally speaking, transition economies emerging from the former Soviet Union have done least well with transition, while those of Central and Eastern Europe have done the best. 4. Capitalism relies primarily on material incentives, while planned socialism and...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT