Question

Give me at least 6 in vivo and in vitro bioassays about amoxicillin. Give me the original source (at least 6) and briefly explain each bioassay  

Answer 1

A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues. Bioassays are quantitative biological assays used to estimate the potency of agents by observing their effects on living animals (in vivo) or tissue/cell culture systems (in vitro).
in vitro activity is quite similar to ampicillin, but it produces higher serum levels after oral administration. The mean peak serum levels of amoxicillin in 11 normal volunteers were 2.30 μg/ml after 125 mg, 3.43 μg/ml after 250 mg, 6.75 μg/ml after 500 mg, and 9.90 μg/ml after 1 g.