Question

What is the function of N5,N10-methylene tetrahydrofolate in the enzyme DNA Photolyase? A) It catalyzes the...

What is the function of N5,N10-methylene tetrahydrofolate in the enzyme DNA Photolyase?

A) It catalyzes the transfer of a hydroxyethyl group to DNA

B) It catalyzes the transfer of a methyl group to DNA

C) It catalyzes electron-transfer to FAD

D) It catalyzes energy-transfer to FAD

E) It catalyzes energy-transfer to pyrimidine dimers

Homework Answers

Answer #1

Answer. (E)

Pyrimidine dimers are formed due to exposure to UV light between the adjacent pyrimidines.

DNA photolyase are 55-65 KDa enzymes which catalyze the breakdown of these dimers which may pose a problem and may lead to frameshift or halting of replication or transcription. This may lead to cell death.

Its substrate speciifcity is due to recognition of the phosphodiester backbone and not by sequence specificty.

It involves the use of 2 cofactors that act as a chromophore -

FADH2

N5, N10- Methylene THF

N5, N10- Methylene THF absorbs a photon of light and transfers it to FADH2 via dipole-dipole intercations. FADH2 further transfers the enrgy to the pyrimidine dimer and so leads to its breakdown.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
What is the funcional of the enzyme DNA polymerase in replication? A) It reads the sequence...
What is the funcional of the enzyme DNA polymerase in replication? A) It reads the sequence of nucleotides on the parental strand of DNA and catalyzes the polymerization of a complementary daughter DNA strand. B) Its reads codond on a DNA molecule and catalyzes the polymerization of a complementary mRNA strand, C) It unwinds the double helix of DNA and separetes the two strand. D) It connects the short Okazaki fragments formed in the lagging strand. E) It carries the...
1- How is mRNA made from DNA? What enzyme catalyzes this reaction? 2- How does the...
1- How is mRNA made from DNA? What enzyme catalyzes this reaction? 2- How does the enzyme know where to start and stop transcription?
What enzyme is responsible for DNA replication? Select one: a. RNA polymerase b. DNA ligase c....
What enzyme is responsible for DNA replication? Select one: a. RNA polymerase b. DNA ligase c. EcoR1 d. DNA polymerase e. Reverse transcriptase
Where does the enzyme Lysozyme that catalyzes the destruction of the cell walls cleaves? A -...
Where does the enzyme Lysozyme that catalyzes the destruction of the cell walls cleaves? A - Lysozyme is a DD-transpeptidase that cleaves the cross-linked peptidoglycan chains. B - Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid (NAM) and N-acetyl-D-glucosamine (NAG) residues in peptidoglycan. C - Lysozyme forms a peptide bond between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water...
topoisomerase has what function? _______ A) elongation of DNA at a replication fork by adding nucleotides...
topoisomerase has what function? _______ A) elongation of DNA at a replication fork by adding nucleotides to the existing chain B) unwinding of the double helix C) relieving strain in the DNA ahead of the rep fork D) stabilizing single stranded DNA at the Rep.fork E) addition of methyl groups to bases of DNA Explain why C is correct and why the other choices are incorrect as well as mention the names of the enzymes for the indicated function
Under physiological conditions, most DNA exist in which form? a. DNA A b. b. DNA B...
Under physiological conditions, most DNA exist in which form? a. DNA A b. b. DNA B c. c. DNA C d. d. DNA Y e. DNA Z What type of RNAs directs the methylation of eukaryotic rRNA? a. Small nucleolar b. small nuclear c. ribozyme d. pre mRNA e. miRNA Ultra violet light causes formation of (a) thymidine dimers (b) 6’-4’ photoproduct (c) cyclobutane ring (d) all of the above (e) both ‘a’ and ‘b Which of the following enzymes...
The prokaryotic replication enzyme that removes and replaces primers is _______. a. ligase b. DNA polymerase...
The prokaryotic replication enzyme that removes and replaces primers is _______. a. ligase b. DNA polymerase I c. primase d. DNA polymerase II Primers are found on: a. only Okazaki fragments. b. both the leading and lagging strands. c. only the leading strand. d. only the lagging strand. e. DNA polymerase III. Which replication enzyme seals the nicks between Okazaki fragments? a. Primase b. DNA polymerase I c. DNA LIgase d. Topoisomerase The first step in the replication of DNA...
You decide to reproduce Reaction #2 in three test tubes. (Reaction #2, Enzyme E2 catalyzes an...
You decide to reproduce Reaction #2 in three test tubes. (Reaction #2, Enzyme E2 catalyzes an energy-requiring reaction that uses Compounds C and D as substrates to produce Compound E). You may assume that this biological reaction occurs at 37 degree celcius and a pH of 7.4 under normal conditions. -Test tube #1: You perform the reaction at 70 degrees celcius and a pH of 7.4 and observe that no Compound E is produced. When the temperature is brought to...
1. Incubating a competent strain of Escherichia coli with DNA in the form of a plasmid...
1. Incubating a competent strain of Escherichia coli with DNA in the form of a plasmid could lead to: Group of answer choices A. Transformation B. Conjugation C. Transduction D. Vertical gene transfer 2. During DNA replication the lagging strand is synthesized: Group of answer choices A. Continuously B. In Okazaki fragments C. In the same direction as the advancing replication fork D. From 3' to 5' 3. Which enzyme is responsible for linking Okazaki fragments in a newly created...
86. What attracts or directs the synthesis enzyme to the template in Translation? a. Start Codon...
86. What attracts or directs the synthesis enzyme to the template in Translation? a. Start Codon b. 5'-cap c. Primer d. Promoter e. Poly-A Tail 92. Which of the following is the description for Catabolic Reactions? a. the energy of movement b. the breaking down of complex molecules into simpler ones c. energy converted from one form to another d. energy is neither created nor destroyed e. the linking of simple molecules to form complex molecules 93. Which of the...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT