Gene duplication events occur by variety of mechanisms including ectopic recombination, aneuploidization, polyploidization and DNA replication errors. The duplicated genes can then diverge, producing pseudogenes, subfunctionalized genes, and neofunctionalized genes. Such gene duplication events produce which class of homologs?
a. orthologs
b. paralogs
c. metalogs
d. hemilogs
Option b-Paralogs
Paralogue is a gene that is related to another gene in the same organism by descent from a single ancestral gene that was duplicated and that may have a different DNA sequence and biological function.
Orthologs are genes that are related by vertical descent from a common ancestor and encode proteins with the same function in different species.
Two genes are 'orthologs' if they diverged due to a speciation event; they are 'paralogs' if they diverged due to duplication within a lineage.
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