Question

The bacterial DNA Gyrase is a_____________ type II topoisomerase that relives the strain of the supercoiled...

The bacterial DNA Gyrase is a_____________

type II topoisomerase that relives the strain of the supercoiled DNA at the replication fork.

type II topoisomerase that unwind the two DNA strands from each other to allow DNA replication

type I topoisomerase that relives the strain of the supercoiled DNA ahead of the replication fork.

type II topoisomerase that relives the strain of the supercoiled DNA and is localized at the replication fork.

type II topoisomerase that relives the strain of the supercoiled DNA an is localized ahead of the replication fork.
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Answer #1

DNA gyrase is a toposiomerase 2 enzyme. It makes a transient double stranded break in the ahead of replication fork. This leads to break the helix and forma a covalent linkage to both strands. It removes the strain from the double stranded DNA which is created by the supercoiling in DNA during their unwinding. That's why most appropriate answer is:

type II topoisomerase that relives the strain of the supercoiled DNA an is localized ahead of the replication fork.

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