Question

Which of the following statements regarding indels is FALSE?

		Indels have the ability to distort the reading frame to varying degrees of severity.
		It’s possible for indel events to cancel one another out which would then leave the reading frame undisturbed.
		A triple insertion is more harmful to a reading frame than a triple deletion.
		Indels can happen in areas outside of the reading frame.
		There are no false statements provided.

Answer 1

False- A triple insertion is more harmful to a reading frame than a triple deletion.

Both changes are equally harmful. Addition of 3 nucleotides will insert an amino acid and deletion of three nucleotides will delete an amino acid.

True- Indels have the ability to distort the reading frame to varying degrees of severity. Indels are additions or deletions which completely change the reading frame.

Indels can happen in areas outside of the reading frame.-True

Mutations can occur anywhere within the reading frame or outside it..

It’s possible for indel events to cancel one another out which would then leave the reading frame undisturbed.-true

Addition and deletion together may balance the reading frame.