Question

A mutation in chaperone proteins within the chloroplast prevents proper folding of rubisco. How would this...

A mutation in chaperone proteins within the chloroplast prevents proper folding of rubisco. How would this impact the Calvin Cycle? How is this process related to protein synthesis and transport?

Homework Answers

Answer #1

RUBISCO is the most abundant enzyme on the earth. It catalyzes the carboxylation of RUBP to produce 3-PG in C3, C4, and CAM plants. It is essential for the Calvin cycle i.e. light independnet reactions to reduce CO2 to carbohydrate.
If a mutation alters the structure of RUBISCO, it would reduce/eliminate the activity of RUBISCO (i.e. protein function is dependnet on its native conformation).

The mutation is affecting the protein folding.
So, it does not affect the protein synthesis or localization (Localization may or may not be affected).

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