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compare lysosomes and proteasomes.

compare lysosomes and proteasomes.

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Proteasome lysosome
Degrade only ubiquitinated proteins do not requires ubiquitin for degradation
Requires ubiquitin ligase no need of ubiquitin ligase
These are the protein complexes These are the cell organelles
Present in eukaryotes, archaea, and in few bacteria present in only eukaryotes
Contains only proteases and can degrade only protein Contains acid hydrolases that can digest any biomolecule
Degrade nuclear, ER and cytosolic proteins Degrade extracellular proteins deliverd by endocytosis
Do not participate in antigen processing and presentation participate in antigen processing and presentation
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