Which of the following best describes an attenuated vaccine?
a. |
The use of a non-pathogen into which surface antigen genes have been cloned. |
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b. |
Use of mutated or weakened live strains to stimulate immunity. |
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c. |
The use of one purified component of an infectious agent in order to stimulate immunity. |
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d. |
The use of denaturants to kill the infectious agent so it does not cause infection. |
Attenuated vaccines are those vaccine which are prepared by reducing the virulence of pathogen so that it is not able to cause disease anymore but is still alive. These vaccines can be created by inducing a mutation in the genes responsible for virulence or altering the expression of genes by cultivating the virus under such circumstances where they generally do not grow.
Non-pathogenic bacteria are not immunogenic
If vaccine are made by purified compound of virus it is a toxoid
And if organism is killed it is type of inactivated or killed vaccines
So option B is correct
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