Question

The signal sequence for import of a protein into the mitochondria is a. hydrophobic beta-sheet b.KDEL...

The signal sequence for import of a protein into the mitochondria is

a. hydrophobic beta-sheet
b.KDEL
c.hydrophobic alpha-helix
d.amphipathic alpha helix

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

D. The signal sequence for import of a protein into the mitochondria is amphipathic alpha helix.

The signal sequence for importing proteins to mitochondria is an amino acid chain in the N-terminal sequence of the polypeptide. The length is about 20-50 residues.

This sequence has a tendency to fold into an alpha helical structure having positive charged amino acids like Arg and Lys residues at one side and hydrophobic amino acids on the other side. The presence of both residues makes this an amphipathic helix. The signal sequence is recognized and transported to mitochondrial matrix where the sequence is cut off by a signal peptidase.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
1.. Protein X has a single N-terminal ER signal sequence, while protein Y has a single...
1.. Protein X has a single N-terminal ER signal sequence, while protein Y has a single internal ER signal sequence. Which of these two proteins will be found in the ER lumen (Answer "X" or "Y")? 2. Protein A has an N-terminal ER signal sequence and one stop transfer sequence, while Protein B has an internal ER signal sequence and one stop transfer sequence. Which of these two proteins will have two transmembrane domains once its translocation is complete (Answer...
1.. Protein X has a single N-terminal ER signal sequence, while protein Y has a single...
1.. Protein X has a single N-terminal ER signal sequence, while protein Y has a single internal ER signal sequence. Which of these two proteins will be found in the ER lumen (Answer "X" or "Y")? 2. Protein A has an N-terminal ER signal sequence and one stop transfer sequence, while Protein B has an internal ER signal sequence and one stop transfer sequence. Which of these two proteins will have two transmembrane domains once its translocation is complete (Answer...
Which of the following statements describes a typical feature of protein import into mitochondria? A. Proteins...
Which of the following statements describes a typical feature of protein import into mitochondria? A. Proteins are imported in a fully folded state B. Protein import is driven by ATP hydrolysis C. Protein import involves a chaperone that keeps the protein unfolded in the cytosol D. The entire process (from signal sequence recognition to signal peptide cleavage) does not require any energy E. Protein depends on diffusion of proteins through porins, followed by active import into the mito matrix through...
Which of the following statements describes a typical feature of protein import into mitochondria? A. Proteins...
Which of the following statements describes a typical feature of protein import into mitochondria? A. Proteins are imported in a fully folded state B. Protein import is driven by ATP hydrolysis C. Protein import involves a chaperone that keeps the protein unfolded in the cytosol D. The entire process (from signal sequence recognition to signal peptide cleavage) does not require any energy E. Protein depends on diffusion of proteins through porins, followed by active import into the mito matrix through...
1. Which cytosolic factor is most likely to associate with the signal sequence of a protein...
1. Which cytosolic factor is most likely to associate with the signal sequence of a protein that is targeted co-translationally to the ER? A chaperone of the Hsp70 family The translocation channel The ribosome Signal recognition particle (SRP) Signal peptidase 2. What is the most likely fate of a protein with an N-terminal hydrophobic sorting signal and an additional internal hydrophobic domain of 22 amino acids? The protein stays in the cytosol The protein is transported to mitochondria Because the...
What is the typical role of a sorting receptor? A. it binds to the signal sequence...
What is the typical role of a sorting receptor? A. it binds to the signal sequence of a protein and targets the protein for degradation. B. It binds to the signal sequence of a protein and targets the protein to a machinery that moves the protein into a new location. *** I think this is the answer C. It cleaves off the signal sequence D. It binds the signal sequence only in the presence of ATP E. It recognizes a...
which of the following is not required for the transport of a protein into the mitochondria?...
which of the following is not required for the transport of a protein into the mitochondria? 1. translaton finished in the cytoplasm 2. translocation channel 3. Ran- Gtase 4. signal sequence 5. Receptor
True or False: If a protein has a signal sequence for synthesis into the ER, but...
True or False: If a protein has a signal sequence for synthesis into the ER, but the sequence is NOT at the N-terminal, then after synthesis the N-terminal will either be in the lumen or outside the cell If false, where would the protein be?
In which way does peroxisomal protein import differ from mitochondrial protein import? A. Ubiquitination is a...
In which way does peroxisomal protein import differ from mitochondrial protein import? A. Ubiquitination is a key step in receptor cycling B. Peroxisomal proteins do not requires signal sequences for import C. Peroxisomal protein import is co-translational D. Peroxisomes use the same mechanism for import of matrix and membrane proteins
Imagine a transmembrane protein made of 7 alpha helices. This protein functions as a pore that...
Imagine a transmembrane protein made of 7 alpha helices. This protein functions as a pore that allows Cl- ions to pass through the membrane. Each alpha helix has hydrophobic amino acids on one surface and hydrophilic amino acids on the opposite surface. Describe how these helices are likely arranged in the membrane.
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT