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If DNA replication were continuous on both strands, which of the following would not be observed/required?...

If DNA replication were continuous on both strands, which of the following would not be observed/required? A. Okazaki fragments B. Supercoiling of the DNA C. Replication fork D. Primers E. Both A and D

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Answer #1

1. DNA replication takes place on leading strand continuously in 3' -> 5' direction. This is initiated by a primer which produce continuous nucleotide strand in 5' -> 3' direction.

2. DNA replication takes place on lagging strand discontinuously in 3'-> 5' direction. This is initiated by multiple primers which produces small nucleotide fragments (100-200) known as Okazaki fragments.

If DNA replication occurs continously on both the strands then 2 primers are required on both strands (Leading and lagging) and Okazaki fragments are not formed.

So, Answer is Option 'A' - Okazaki fragments not observed.

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