Question

1. Quaternary structure

a. cannot be denatured

b. absolutely require multiple protein subunits

c. is exhibited by myoglobin and hemoglobin

d. all of the above

e. none of the above

2. With respect to hemoglobin

a. Fe is the form of iron that carries oxygen

b. 2 3 bpg favors tighter binding of oxygen

c. at the concentration of oxygen in tissues hemoglobin has more oxygen affinity that myoglobin

d. at the concentration of oxygen in lungs myoglobin has about the same affinity for oxygen as hemoglobin

e. all the above

f. none of the above

3. With respect to the bohr effect

a. co2 is produced in tissues and carried to the lungs

b. ph 7.8 favors more oxygen binding by hemoglobin that ph 7.6

c. it results partly from protons adding onto ionizable groups

d. all of the above

e. none of the above

Answer 1

Q1. Option B is correct. Absolutely require multiple protein subunits.

Quaternary protein can be easily denatured example by heating. Myoglobin is tertiary structure but hemoglobin is quaternary structure.

Q2. Option F is wrong.

Fe2+ is the form that carries O2.

2,3-BPG favours dissociation of O2 .

Myoglobin is always have hight affinity for O2 than hemoglobin becasue of the proximal Histidine residue.

Q3. Option D.is correct. All are correct.

CO2 is produced in tissues and carried to the lungs. Bohrs effect is enhanced by lower pH, increase in concentration of CO2, decrease in concentration of O2, high 2.3-BPG.