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Hemophilia is an X-linked recessive disorder. If a woman who is a carrier is planning to...

Hemophilia is an X-linked recessive disorder. If a woman who is a carrier is planning to have children with a man who has the disorder, what is the probability that their first child will be a phenotypically normal girl? Show your work

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Answer #1

The probability of a phenotypically normal for this couple can be understood by the following cross:

Let 'h' represent the allele which codes for the trait.

Parents :

Mother : XhX (carrier)

Father : XhY(affected)

Gametes: Xh,X,Xh,Y

Xh X
Xh XhXh(affected girl) XhX(carrier female)
Y XhY(affected boy) XY(normal male)

Carrier females does not phenotypically show the disease . Therefore the probability of a carrier is 25% who is phenotypically normal.

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