Question

All questions needed. No explanation needed, just true or false. Will give humbe up for correct answers.

a. When traction is less than contraction, the cell is spreading.

True or false

b. Cells that spread on three dimensional substrates maintain differentiated function better than two dimensional substrates.

True or false

c. Cell spreading area is proportional to cell proliferation.

True ir false

d. Proliferative activity of cells can be mudulated by receptor/ligand interactions.

True or false

e. Cells will not adapt to their environment.

True or false

Answer 1

A. True. ( Contractile force increases significantly when cells are spreading, whereas traction is unnecessary for cell spreading or minimum traction is needed for it.)

B. True (in two dimensional substrates , cells are grown in flat and stretched structure, whereas in three dimensional substrates, they are formed in aggregates or spheroids. Thus , they better mimic the in vivo condition.)

C. True (cell spreading is coupled to cell proliferation. )

D. True

E. False (cell adapts to various varying environmental changes. These adaption could be physiological or pathological in nature.)