Question

Explain how the expected F1 results differ depending on whether the genes are x-linked or autosomal.

Answer 1

If a disease is showing sex linked inheritance it defiantly differ in its way of transmitting to the next generations from the autosomal diseases. In autosomal diseases receprocal crosses would give the similar offspring. But in sex linked inheritance receprocal crosses resulted in different progeny.

For example let's considera gene-A responsible for enzyme for which nonfunctional form causes disease if we consider a cross

(Female) aa. X. AA (male)

Progeny all Aa having no disease irrespective of the gender.

But in x linked cromosomal disease's

If female effected

(Female) xx. X. XY(male)

Progeny Xx (female) and xY (male) male effected and female are not effected but all female are carriers

If male effected

XX. X. xY

Progeny Xx all female are carrier's and XY male not effected but xY male are effected.