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3. Explain the volume of distribution and its importance in pharmacology. If Vd of a drug...

3. Explain the volume of distribution and its importance in pharmacology. If Vd of a drug is 35 L, in which compartments does the drug distribute in?
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Volume of distribution which is denoted as Vd is the apparent volume at which the drug dissolves and reaches equilibrium. Vd is calculated by dividing the concentration of the drug in the body by the weight of drug in the body. [Vd=concentration/weight]. However in human body after the drug has been injected, it often travels to various organs which it needs to target. These organs can be the brain, the liver, etc. However, as the drug travels its concentration will decrease over time and its Vd will increase. Vd is very crucial in pharmacology because it gives an idea about the drug and it's dissolving rate, which makes the mechanism of the drug clear. In the given question, it is said that the Vd of the drug is 35mL. As, the value of Vd is small, we should conclude that the drug has not dissolved to many organs. It's concentration will probably be on the higher side.

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