In most animals, only the conserved seed sequence of the microRNA needs to be perfectly complementary to the target gene. The other regions may or may not be exactly complementary.
There are many somatic cell mutations that occur daily in multicellular organisms, most of which are point mutations. All mutations are not lethal or disruptive and hence do not require special attention by the cell. Most mutations of this sort in genes show no visible affects are go undeteced.
Each cell type is designated to perform certain specific activities. An extracellular signal/stimulus will cause each cell type to react differently, thereby making them specialized for certain functions.
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