What is emigration of leukocytes from the microcirculation, their accumulation at the focus of injury, and their activation to eliminate the offending agent termed as?
A) PHAGOCYTOSIS
B) Extravasation
C)Exudation
D)chemotaxis
A patient age 25 was prescribed ibuprofein after undergoing a flap surgery. Which one of the following chemical mediator is inhibited to provide pain relief?
A) prostaglandin
B) HISTAMIN
C)Leukotrine
D)Bradykinin
1. Answer: Option B
is correct
Explanation:
Extravasation = Diapedesis = Leukocyte adhesion cascade
It refers to the movement of leukocytes from their microcirculation
to the site of injury.
2. Answer: Option A
is correct
Explanation:
Ibuprofen is a nonsteroidal anti-inflammatory drug
It is an inhibitor of the Cyclo-oxygenase enzyme.
Cyclo-oxygenase is involved in the biosynthesis of Prostaglandins
via the Arachidonic acid pathway.
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