Question

Does Neuropeptide Y (NPY) improve learning and memory, or does it impair learning and memory?

Answer 1

NPY act as a neuromodulator , neuroplasticity and in memory.it is released by gabanergic neurons and have receptors as Y1 and Y2. NPY act as both ways in enhancing memory as well as impairing it. This depends on the part of brain , NPYrecepters, phase. It acts as resilience factor by impairing stressful , depressed memoried.It acts by working on Y1 receptors in amygdala.

NPY also acts enhances consolidation and retention of models depending upon septial and discriminative type of explicit memory in this case the work is done on Y2receotors located in hippocampal reason. So it works in both ways also enhance the memory and learning and impair the memory and learning.