Which of the following statements about the Lac operon is correct?
Group of answer choices
The Lac promoter is weak because its sequence deviates significantly from the consensus sequence.
The Lac promoter is weak because it requires cAMP for transcription.
The Lac promoter is strong because its sequence does not deviate greatly from the consensus sequence.
The Lac promoter is strong so it requires a repressor for negative control.
ANSWER :- a.) The lac promoter is weak because it's sequence deviates significantly from the consensus sequence.
A promoter is considered weak or strong based on the affinity for RNA polymerase and the sigma factor. This means the consensus sequence of promoter should match that of the RNA polymerase. If it doesn't exactly match, we can say that the promoter is weak. A weak promoter gives low Transcription and thus low levels of protein product.
The lac promoter is not a particularly strong promoter, and mutations have been obtained that either can increase or decrease its efficiency of initiating Transcription. Base substitution that make the promoter sequence more similar to the consensus generate a stronger promoter whereas those that make the promoter less similar to the consensus generate a weaker promoter.
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