Question

Can miRNA target useful mRNA transcripts in human beings?

Can you give a down to earth explanation/explanation? Or a decent hint at how to think about the question--I just don't get how to answer it.

Answer 1

Question is asking that can microRNA bind and degrades to useful mRNA transcripts?

Its simple answer is Yes.

• For regulation of gene expression at posttranscriptional level it is useful.
• This is also called as silencing of gene and its action by binding small 22 nucleotide long non coding RNA molecules to mRNA.
• After binding unusual bonding of bases leads to degradation of miRNA-mRNA complex by some nucleases.
• So in human MicroRNAs have been been demonstrated to play a major role in a wide range of developmental processes including metabolism, cell proliferation,apoptosis, developmentl timing, and neuronal cell fate as well as cancer.
• So miRNA using gene regulation can be done by using miRNA to rwgulate growth developmwnt and cancer as well as some diseases.