Classify each of the following membrane proteins into transporter, receptor, membrane fusion, membrane remodeling:
A) ATP synthase
B) Tyrosine kinases
C) Na+/K+ ATPase
D) Pancreatic Lipase
E) Synaptotagmin
F) Flipasses
G) GPCRs
H) SNAREs
Answer :
A)
ATP Synthase - membrane fusion protein
Fusion of a and c subunits by ATP Synthase in inner mitochondrial membrane.
B)
Tyrosine Kinase - Receptor membrane proteins
Receptor tyrosine kinases are high affinity cell surface receptors for many polypeptide growth factors and cytokines and hormones.
C)
Na K ATP ase - Transporter membrane protein
The are also called sodium potassium pump.
D)
Pancreatic lipase - receptor membrane proteins
Also as membrane fusion proteins
Ligand factor for receptor mediated lipoprotein uptake.
E)
Synaptotagmin - membrane fusion protein
In neurons it triggers complete fusion of vesicles with target membrane.
F)
Flipasses - transport membrane proteins
Transmembrane lipid transporter proteins.
G)
GPCRs - receptor membrane proteins.
They are G Protein Coupled Receptors.
H)
SNARES - fusion membrane protein
Fusion of vesicles with target membrane.
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