Question

Which of these B vitamins is not part of a coenzyme in the PDHC mechanism?

A) Riboflavin (Vitamin B2)

B) Biotin (Vitamin B7)

C) Thiamine (Vitamin B1)

D) Niacin (Vitamin B3)

Answer 1

A)The B vitamins which are not part of coenzyme in the Pyruvate dehydrogenase complex is Biotin(vitaminB7)

Biotin functions as a cofactor that aids in the transfer of CO2 groups to various target macromolecules. Biotin has nine host enzymes with which it is associated. Humans only have four of these enzymes: Pyruvate carboxylase

PHDC is a multifunctional enzyme complex which catalyses oxidative decarboxylation of pyruvate to acetyl-CoA,NADH,and CO2

PHDC is a complexof three enzymes that converts pyruvate into acetyl-coA by a process calledpyruvate decarboxylation pyruvate decarboxylation is also known as the pyruvate dehydrogenase reaction because it also involves the oxidation of pyruvate