Question

Consider the data from Framingham Heart Study as described by Shurleff (1970, 1974). The following table gives the 16-year incidence of myocardial infarction (MI) in Framingham, MA, for men aged 35 to 44 years, by level of serum cholesterol. The data are shown below:

SC (mg%)         MI+     MI-           Total

>250      10        125             135

<250      21        449             470

Total       31     574              605

Carry out appropriate test to evaluate possible association between SC and incidence of MI, and calculate 95% confidence intervals for risk difference (RD), risk ratio (RR).

Answer 1