Question

A woman with average height, and type A- blood, and a man with type B+ blood and achondroplastic dwarfism, have a daughter with type O- blood, average height and cystic fibrosis. Write the genotype of the father, starting with ABO, Rh, height, cystic fibrosis, and sex. Be sure to follow the nomenclature rules. (For example: for a blue-eyed person with hairless knuckles, you would write b/b, kn/kn. For a brown-eyed person with hairy knuckles, write B/B, Kn/Kn, if the person is known to be homozygous; B/b, Kn/kn, if the person is known to be heterozygous; or B/?, Kn/?, if the exact genotype of the person is not clearly known. Note the use of punctuation.)

Answer 1

Let average heightbis encoded by H allele. It is dominant ovet h allele.

The man is with achondroplastic dwarfism and has B+ blood group. And the daughter is with average height, O- blood group and hvaing cystic fibrosis.

The woman with average height, and type A- blood.

Man genotype:

It means the man has IB/i genotype for blood group. Because O blood group is found in daughter.

The Rh factor in man is Rh+/Rh-. Because the man has B+ and he passes Rh- allele in the daughter.

The man have achondroplastic dwarfism. It means the genotype of man is h/h.

The man and woman is normal. But they have cystic fibrosis trait bearing daughter. It means man has genotype of C/c.

The overall genotype of man is:

IB/i, Rh+/Rh-, h/h, C/c, X/Y