Question

What would not occur if PLCzeta levels did not rise inside ova after fertilization. Explain why

Answer 1

The PLC-zeta is responsible for the activation of the oocyte and initiation of embryonic development.

When sperms enters the oocyte, there is rise in level of cytosolic calcium ions. This calcium ions entry is responsible for the activation of oocytes.

For movement of calcium ions, there is a requirement of PLC-zeta.

PLC-zeta is a testēs specific phopholipase C enzyme.

This enzyme catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphste.

Hydrolysis of this compound cause increase in cytosolic calcium.

Thus, if PLC-zeta level does not rise after fertilization, then oocytes activation will not occur and embryo will not develop.