Question

During excitation, the voltage fluctuation caused by K⁺ entering and Na⁺ leaving the cell through the sarcolemma is called the end-plate potential.

TRUE

OR

FALSE

Answer 1

False.

End plate potential is caused by the depolarization of sarcolemma at the neuromuscular junction due to release of neurotransmitters from the synapse. The presynaptic neurons release vesicles containing neurotransmitter, acetylcholine which stimulates the postsynaptic membrane for depolarization. It opens calcium channels in the sarcolemma which carries action potential through the skeletal muscle. Voltage fluctuations due to K+ entering and Na+ leaving the cell is responsible for resting membrane potential.