Question

Comparison of glycogen synthesis and breakdown in muscle and liver reveals:

	A.	Stimulation of glycogen breakdown in both tissues by epinephrine leads to enhanced glucose uptake by liver cells and enhanced glucose export from muscle cells.
	B.	Stimulation of glycogen synthesis by insulin in both tissues leads to glycogenolysis in both liver and muscle.
	C.	Inhibition of glycogen synthesis in both tissues by epinephrine leads to glycogenolysis in both liver and muscle.
	D.	Stimulation of glycogen synthesis by insulin in both tissues is accompanied by decreased glycogenolysis.
	E.	Epinephrine stimulates glycogen uptake in liver and breakdown in muscle.

Answer 1

Correct statement is answer D.

Stimulation of glycogen synthesis by insulin in both tissues is accompanied by decreased glycogenolysis.

When blood glucose levels are in excess, insulin stimulates the production of glycogen which stores extra glucose in liver and muscle cells.

Epinephrine stimulates glycogen breakdown but not equally in both tissues. It stimulates glycogenolysis in muscle cells more as compared to liver cells. Liver cells work better with glucagon which is a peptide hormone whereas epinephrine is a catecholamine.