Question

A patient is admitted to hospital with organophosphate poisoning. Their symptoms include difficulty breathing and a...

A patient is admitted to hospital with organophosphate poisoning. Their symptoms include difficulty breathing and a low heart rate.

a) Describe the mechanism of action of this poison.

b) Explain why the patient has these symptoms, and identify the receptors and second messengers that are involved.

c) Identify a drug that could be used to treat organophosphate poisoning, and explain why this treatment would be effective.

d) What would happen if a patient with organophosphate poisoning was given rocuronium? Explain your answer.

Science   Anatomy-And-Physiology   
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Homework Answers

Answer #1

Answer a.

The poison is anticholinesterase. It inhibits the degradation of acetylcholine and more acetylcholine is available to show cholinergic effects at synaptic cleft.

Answer b.

The person is suffering from bradycardia. This is due to activation of muscarinic receptors.It decreases entry of calcium ions in cardiocytes and causes bradycardia.

Answer c.

The drug Atropine is use in treatment of anticholinesterase poisoning. atropine is antagonist of acetylcholine.

It inhibits binding of acetylcholine to muscarinic receptors.

Answer d.

Rocuronium is a neuromuscular blocked. If it is given it will cause a de create in cardiac conduction that will ultimately cause decrease sinking and shopping of heart.

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