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What neurotransmitter does a somatic motor neuron release into the synapse with a skeletal muscle fiber?...

What neurotransmitter does a somatic motor neuron release into the synapse with a skeletal muscle fiber? What is the effect on the membrane potential of the muscle fiber? How is ACh removed from the synapse?

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Answer #1
  • The nerve action that is started in the cell body of motor neuron of spinal chord propagates throughout the ventral route and moves towards motor neuron synaptic terminal. Due to propagation of action potential, acetylcholine is released in synaptic cleft.
  • The release of Acetylcholine leads to the depolarization of the membrane and an increase in spike frequency.
  • The acetylcholine is removed by diffusion, reuptake by the neuron and by degradation of acetylcholine to acetate and choline by enzyme acetylcholinesterase.
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